Diffuse skin hyperpigmentation associated with chronic minocycline use in a patient with prosthetic joint infection

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Diffuse skin hyperpigmentation associated with chronic minocycline use in a patient with prosthetic joint infection

Cutaneous hyperpigmentation is a recognized adverse effect of chronic minocycline use occurring in up to 50% of patients. In this report we present a rare case of extensive skin hyperpigmentation involving both lower extremities in a patient receiving long term minocycline. The patient was receiving minocycline as suppression for chronic prosthetic joint infection. Risk factors associated with ...

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INTRODUCTION While epidermal growth factor receptor (EGFR) inhibitors have improved progression-free survival in patients with non-small cell lung cancer (NSCLC), one of the most common adverse effects is papulopustular skin eruption, which is frequently severe enough to be treated with oral minocycline or doxycycline. CASE We present a case of an 87-year-old man who developed a severe papulo...

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Minocycline-Induced Cutaneous Hyperpigmentation in an Orthopedic Patient Population

Background.  The objectives of this study were to estimate the incidence and evaluate risk factors for development of minocycline-induced cutaneous hyperpigmentation in patients with orthopedic infections. Methods.  Patients with orthopedic infections evaluated at Mayo Clinic (Rochester, MN) and treated with minocycline from 1 January 2002 to 31 December 2011 were retrospectively identified. Lo...

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ژورنال

عنوان ژورنال: IDCases

سال: 2017

ISSN: 2214-2509

DOI: 10.1016/j.idcr.2016.12.003